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About Pratico Lab

Dr. Domenico Pratico researcher team photo

Pratico Lab focuses on clinical pharmacology, specifically investigating the cellular and molecular aspects of cell oxidative biology. The lab has a keen interest in small molecules like bioactive oxidized lipids and their significance as biomarkers, mediators of cellular and molecular events involved in the pathogenesis of clinical conditions, and potential therapeutic targets for human diseases.

 

The research extends to multiple disciplines including aging, cardiovascular diseases, and neurodegeneration. Cellular and animal models of human diseases are employed, with an emphasis on translating observations into a better understanding of human physiology and pathology. The lab is dedicated to fostering high-quality collaborative scientific research while providing exceptional teaching and mentoring for young scientists.

Dr. Domenico Pratico's research area is clinical pharmacology with a special focus on the cellular and molecular aspects of cell oxidative biology and a particular interest in small molecules such as bioactive oxidized lipids.

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This area is very broad and extends to multiple disciplines including aging, cardiovascular diseases as well as neurodegeneration. Our work in the biology of oxidized bioactive lipids has significantly contributed to the current understanding of their importance as biomarkers, mediators of cellular and molecular events involved in the pathogenesis of several clinical conditions, and therapeutic targets for preventing and treating human diseases.

Dr. Domenico Pratico

Founding Director and Professor,

Alzheimer's Center

at Temple University

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